Chapter 1: An Overview of Cells At Work!

"Cells At Work!" is a distinctive anime that expertly melds educational content with engaging entertainment.

Initially airing in July 2018 under the title "Hataraku Saibou," this series emerged just prior to the global Covid pandemic. I initially dismissed it, thinking the premise—human cells and pathogens represented as anthropomorphic characters—was far-fetched. My skepticism led me to overlook it, believing that education and entertainment couldn't coexist.

However, the pandemic shifted public interest toward understanding immune systems, propelling "Cells At Work!" into popularity, especially among international audiences. As discussions and reviews on its MyAnimeList page increased, I remained doubtful about its scientific accuracy, concerned that creative liberties might have compromised its educational value.

Then, I discovered YouTube videos featuring doctors reviewing the show, specifically praising its detailed portrayal of the immune system.

Most medical professionals commended it for its accuracy and thorough research. While that might sound dull, I encourage you to view the official trailer, which includes English subtitles:

Having now watched both seasons, along with the specials and the first season of the spin-off "Cells At Work! CODE BLACK," I've observed that the original series takes place in an average human body, while the spin-off depicts a man whose lifestyle choices lead to a deteriorated state of health. While "CODE BLACK" is darker and offers a more realistic perspective, it lacks the production quality of the original, which was created by the esteemed studio David Production.

Chapter 2: Characters and Story Dynamics

The central characters in "Cells At Work!" are Sekkekkyuu AE3803 (Red Cell) and Hakkekkyuu U-1146 (White Cell). Red Cell, a charming and somewhat clumsy character, carries oxygen from the lungs to various body parts and returns carbon dioxide to be exhaled.

One humorous moment occurs when she accidentally opens the wrong door and encounters a sneaky bacterium, leading to a comical interaction where she quickly apologizes and exits.

Red Cell is voiced by the talented Kana Hanazawa, who brings her character to life with her remarkable versatility. In contrast, White Cell, depicted as a fierce neutrophil, often comes to her aid while displaying a ruthless side towards pathogens. This dynamic between the two forms the core of the series.

What I appreciate about "Cells At Work!" is its ability to be both entertaining and educational. It covers various subjects such as immunology and cell biology while presenting them in a light-hearted manner. After each episode, I found myself eager to learn more about the pathogens and immune cells featured.

The macrophages, characterized as polite, tea-loving women from the 19th century, were particularly memorable. Yet, when it comes to dealing with pathogens, they exhibit fierce determination.

David Production's animation quality is exceptional, with excellent voice acting and fitting music that enhances the viewing experience. Notably, the series avoids unnecessary CGI, seamlessly integrating it with the hand-drawn animation style.

In conclusion, I wholeheartedly recommend both seasons for their educational value and enjoyment. The first season comprises 13 episodes, while the second contains 8, with a standout moment being a significant battle against a cancer cell.

General rating: 8.5/10 (original) and 7/10 (CODE BLACK)

For more anime insights, check out my review of "Odd Taxi," a distinctly different series:

Odd Taxi Review A different, highly watchable, quite original anime